Anaemias--Case Studies

Studies in the Anaemias of Infancy and Early Childhood

In Part I of this series we have emphasized the fact that ansemia must be regarded as a disease of the erythron, that is, as a disease which not only may affect the red cells in the circulating blood, but also their precursors in haemopoietic centres of the marrow and elsewhere, although both portions of the erythron do not necessarily suffer to the same extent nor even at the same time. Such a...

The megaloblastic anaemias.

The Sideroblastic Anaemias.

The Spherocytic Haemolytic Anaemias

The diagnosis of haemolytic anaemia is made when circulating red blood cell (RBC) survival is shortened. Today, the laboratory findings in haemolytic anaemia and the distinction between inherited and acquired forms are studied by preclinical medical students the world over. Although haemolytic anaemia is much less common than anaemia as a result of marrow failure or bleeding, general physicians...

Megaloblastic anaemias of gastrointestinal origin.

THERE exist two known anti-megaloblastic substances, vitamin B12 and folic acid. Both of these are absorbed from the small intestine and the body is dependent on their dietary supply to prevent abnormal changes in haemopoiesis. Deficiencies of these compounds may arise in a number of ways, but one important group arises from abnormalities of the small intestine interfering with normal absorptiv...